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Leo Panda

Bioinformatics Research Associate
SKILLS
Python
R
NGS Data Analysis
RNA-seq
Linux & Bash
Workflow Management
EDUCATION
Boston University
BioinformaticsComputational Biology
Master of Science in Bioinformatics
Boston, MASep 2019 - May 2021

Thesis focused on transcriptomic biomarkers and reproducible analysis pipelines for cancer genomics datasets.

University of Massachusetts Amherst
Molecular BiologyComputer Science
Bachelor of Science in Biology
Amherst, MASep 2015 - May 2019

Minor in Computer Science; graduated magna cum laude.

HONORS & AWARDS
Best Poster Award
Graduate Research Fellowship
PROFESSIONAL SUMMARY

Bioinformatics Research Associate with 4+ years of experience analyzing next-generation sequencing data in academic and biotech settings. Skilled in Python, R, RNA-seq, and reproducible workflow development for translational research. Improved data processing efficiency, supported biomarker discovery, and delivered validated results for cross-functional scientific teams.

RESEARCH EXPERIENCE
Transcriptomic Biomarker Discovery in Solid Tumors/Graduate Research Assistant
Boston, MA
Department of Medicine, Cancer Genomics Lab
Sep 2019 - May 2021
  • Analyzed RNA-seq and whole-exome sequencing data from 180 tumor samples to identify expression signatures associated with treatment response across solid tumor cohorts.
  • Developed reproducible Snakemake workflows and QC reports that reduced manual processing time by 35% and improved cross-study consistency for manuscript-ready datasets.
PROFESSIONAL EXPERIENCE
HelixNova Therapeutics
Cambridge, MA
BiotechnologyOncology
Bioinformatics Research Associate
Jun 2022 - Present
NGSPython
  • Built and maintained RNA-seq and targeted DNA sequencing pipelines supporting preclinical oncology programs, reducing average analysis turnaround time from eight days to five.
  • Partnered with scientists and statisticians to analyze 250 plus tumor and cell-line samples, generating differential expression and pathway insights for candidate prioritization.
  • Automated sample metadata validation and quality control checks in Python, decreasing data entry discrepancies by 40% across internal sequencing submissions.
  • Summarized bioinformatics results in technical reports and slide decks for research leadership, contributing to three program review decisions and two IND-enabling studies.
Massachusetts General Hospital
Boston, MA
Academic Medical CenterTranslational Research
Research Bioinformatics Assistant
Jun 2021 - May 2022
RNA-seqR
  • Processed bulk RNA-seq, ChIP-seq, and clinical annotation data for immuno-oncology studies, supporting biomarker evaluation across retrospective patient cohorts.
  • Wrote R scripts for statistical analysis and visualization, shortening recurring reporting cycles by 30% for principal investigators and collaborating clinicians.
  • Coordinated with wet-lab staff to reconcile sequencing batch issues, improving successful downstream analysis rates from 88% to 96% within one year.
  • Contributed curated datasets and methods documentation for two peer-reviewed publications and one national conference poster accepted during the appointment period.
SELECTED PROJECTS
Single-Cell RNA-seq Immune Profiling Workflow
Mar 2024 - May 2024
Project Lead
  • Designed a reproducible single-cell RNA-seq workflow for immune cell annotation and differential abundance analysis across 60 patient-derived tumor samples.
  • Integrated Seurat-based clustering and automated QC thresholds, improving analyst consistency and cutting exploratory processing time by 28%.
  • Delivered publication-ready figures and methods documentation adopted by two internal research teams for follow-on exploratory studies.
KEY ACHIEVEMENTS
Manuscript Contribution

Co-authored 2 peer-reviewed publications in cancer genomics and translational bioinformatics as a contributing analyst.

Reproducibility Improvement

Standardized version-controlled analysis templates adopted across 3 research teams, improving audit readiness and method traceability.

Poster Recognition

Presented biomarker analysis findings at a regional AACR meeting and received Best Poster Award among early-career researchers.

LANGUAGES
English

Native or bilingual proficiency

CERTIFICATIONS
Genomic Data Science Specialization - Johns Hopkins University via Coursera
Aug 2023

Genomic data analysis and computational methods certificate.

Responsible Conduct of Research - CITI Program
Feb 2022

Biomedical research compliance and ethical conduct certification.

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